Fresh air and better houses are weapons in the fight against TB

The disease has been rare in rich countries for 50 years, and one reason is decent housing
Better housing is key to winning the battle against TB. Archive photo: Masixole Feni

Tuberculosis (TB) is second only to Covid as the deadliest infectious disease over the last few years. But only in poorer countries: for more than 50 years, TB has been rare in wealthier countries. One of the reasons for this has been better housing and ventilation.

According to the 2020 Global Tuberculosis Report, eight countries account for two-thirds of all new TB cases: India (26%), Indonesia (9%), China (8%), the Philippines (6%), Pakistan (6%), Nigeria (4%), Bangladesh (4%), and South Africa (4%). South Africa is second only to Lesotho in per capita prevalence.

The Treatment Action Group, a US advocacy organisation, described the Covid years as having “reversed an entire generation of progress”, with global TB deaths estimated to have increased year-on-year for the first time since 2005.

But for more than 50 years, barring an occasional outbreak, TB has been a minor disease in the global north – and this has been achieved without a new vaccine. South Africa has had access to TB medicines, most of them tested in the 1940s through 1960s (the last decade has also seen a few new anti-TB medicines), yet it has been unable to bring the epidemic under control.

A century ago, in 1922, TB was the third leading cause of death in the United States behind heart disease, and pneumonia and influenza. It was responsible for 88,000 deaths, or 8% of all deaths that year. By then TB had already become less deadly; in 1902 and 1912, 11% of all deaths in the United States of America were due to TB.

Over the decades that followed, TB deaths started to become even less prevalent. By 1952, it was the ninth most common cause of death, responsible for 24,000 deaths, or 1.6% of the total, and by 1954 it was no longer in the top ten at all. In 2019, 526 people died from TB in the USA.

South Africa is about a century behind the USA. The latest release by Statistics South Africa on mortality data, for 2018, showed that 6% of the recorded 450,000 deaths that year were from TB.

In a 2015 article, Sabine Hermans, C. Robert Horsburgh Jr., and Robin Wood looked at TB policy over the course of the 20th century in Cape Town, New York and London. They found that each of these three cities implemented key TB control interventions at around the same time. In some cases, like tuberculin testing of cattle, Cape Town was the pioneer. But in spite of measures such as the use of the BCG vaccine in all these cities, only New York and London managed to get TB under control over the course of decades.

Survival rates improved all round with the introduction of TB medicines in the 1950s and 60s. These drastically improved the odds of a patient surviving TB disease.

But treatment and controls had little effect on halting transmission in Cape Town.

Hermans, Horsburgh and Wood’s research shows that living conditions in much of Cape Town, including overcrowded housing and malnutrition, have kept transmission going while it was effectively halted in the first world.

The researchers say that better understanding is needed about the role of separate sleeping spaces for children, good ventilation in transport and schools, and TB screening to interrupt transmission..

A March 2022 review of the WHO Global Tuberculosis 2021 Report in the International Journal of Infectious Disease confirmed the role of poverty in the spread of the disease. “It is certain,” the authors wrote, “that TB care and prevention targets are unlikely to be achieved if large proportions of the populations of the world are allowed to continue languishing in poverty.”

About half of South Africa’s TB cases in 2018 were people living in informal settlements, according to a study in the British Medical Journal.

The same study found that cases among people living in informal settlements could be reduced by 43%, if TB control measures were intensified. These measures might include testing, medical surveillance, and better access to primary healthcare.

A 2018 study found that ending extreme poverty would result in reducing global TB prevalence by a third. Expanding social protection would lead to a 75% reduction in global TB incidence.

Fresh air

The role of fresh air is also vital.

Until recently, it was assumed that only people with symptoms of TB transmitted the infection. But recent research shows that TB, which is spread through breathing — the same way as Covid — can be transmitted by asymptomatic people.

A 2013 paper by Jason R Andrews, Carl Morrow, and Robin Wood modelled the risk of TB transmission across various modes of public transport in South Africa, finding that overcrowded minibus taxis gave commuters the highest risk of acquiring a TB infection.

When GroundUp investigated the quality of air in public transport in Cape Town in 2021, we found that conditions in public transport are primed for the spread of airborne infectious disease.

A 2013 study on TB transmission in traditional homes and shacks in KwaZulu-Natal found that improving ventilation greatly reduced the likelihood of household TB transmission, one of the key means by which TB is spread. But keeping windows and doors open in single-room houses is not always practical in high-crime or very cold environments.

Current TB spending patterns can be made slightly more efficient. A recent study in the Lancet that looked at the spending between 2010 and 2019 found that treatment coverage could be increased by between 12 and 26% for the same amount of spending. Countries that tended to spend more on TB treatment tended to be more efficient, with Nigeria, Mongolia, Indonesia, Ghana, and Laos among the least efficient countries for TB spending.

But this study, too, found “consistently significant negative associations between efficiency and the proportion of urban populations living in slums” – a sign that those governments that succeeded in poverty reduction were also more efficient in fighting TB.

To reduce TB to a minor disease, we have to sort out housing and ventilation, especially on public transport.

This is the second of two articles on TB.

© 2022 GroundUp.

This article was first published here.

COMMENTS   2

Sort by:
  • Oldest first
  • Newest first
  • Top voted

You must be signed in and an Insider Gold subscriber to comment.

SUBSCRIBE NOW SIGN IN

So where is the TB Command Council ??? It was SOOO effective in fighting Covid ne!!

“To reduce TB to a minor disease, we have to sort out housing and ventilation, especially on public transport.”

Public transport does have windows ne — Sorting out the housing part on the transport system might be more of a problem.

You woke academic types have to make up your minds. Scientists predicted that Africa would be the epicenter for covid deaths. The opposite was true. Europe was the epicenter.

It is because Africans live outdoors they said. Their vitamin D levels are high because they are exposed to the sun. Now, the academics claim that these same individuals who escaped covid mortality because they live outdoors, may die of TB because they are cramped indoors.

Just say it like it is – you are clueless and you don’t know. It is OK not to know, but it is not ok to BS everybody.

End of comments.

LATEST CURRENCIES  

USD / ZAR
GBP / ZAR
EUR / ZAR
BTC / USD

Podcasts

Instrument Details  

You do not have any portfolios, please create one here.
You do not have an alert portfolio, please create one here.
INSIDER SUBSCRIPTION APP VIDEOS RADIO / LISTEN LIVE SHOP OFFERS WEBINARS NEWSLETTERS TRENDING

Follow us:

Search Articles:
Click a Company: